Measure the specimen (three dimensions), giving a separate measurement for overlying skin if included. Orient it if sutures/clips/ink present.
Examine the skin surface for scar, ulcer, or other lesions. Examine the external surface of the soft tissue for encapsulation or involvement by tumor.
Ink the resection margins, using different colors if oriented. Follow the guidelines in Skin Excisional Biopsy if applicable.
Serially section the specimen at 0.5-1.0 cm intervals, depending on the size of the specimen (i.e. smaller if small specimen).
Describe the cut surface (color, solid vs. cystic, fatty, fleshy, bulging, soft, necrotic, hemorrhagic, circumscription).
Submit tissue for special studies if indicated. For cytogenetics, unfixed tissue should be used. Cytogenetics help render definitive diagnosis of certain sarcomas (e.g., Ewing’s sarcoma, synovial sarcoma, etc.).
Received without fixative/in formalin, labeled _____ and “_____”, is a __ x __ x __ cm mass of tan-pink soft tissue with a solid, soft tissue tumor mass that comprises most of the specimen. The tumor has a rubbery, firm, variegated, tan and white cut surface with a distinct whirling pattern without necrosis. The closest margin is 0.5cm at the posterior aspect of the tumor. Thin slips of skeletal muscle are lossely attached along one side, designated by a single black suture as “deep margin”. This is uninvolved by tumore. Representative sections, including 40% of the specimen are submitted in cassette #__ - #__.
#__ - #__ = tumor with posterior margin; 1 piece in each.
#__ = anterior margin, shaved; __ pieces.
#__ = deep margin; __ pieces.
#__ = medial margin; __ pieces.
#__ = lateral margin; __ pieces.
#__ = proximal margin; __ pieces.
#__ = distal margin; __ pieces.
#__ - #__ tumor from distal to proximal; 1 piece in each.