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Home --> Grading Schema (main page) --> Placenta |
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Placenta
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Maternal inflammatory response
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Stage |
Suggested Diagnostic Terminology |
Defining Histologic Features |
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1 (Early) |
Acute subchorionitis or chorionitis |
PMN in subchorionic fibrin and/or membrane trophoblast |
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2 (Intermediate) |
Acute chorioamnionitis |
Diffuse-patchy PMN in fibrous chorion and/or amnion |
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3 (Advanced) |
Necrotizing chorioamnionitis |
PMN karyorrhexis, amniocyte necrosis, and/or amnion basement membrane thickening/hypereosinophilia |
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Grade |
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1 (Mild - moderate) |
Mild–moderate |
No special terminology required Not severe as defined below |
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2 (Severe) |
Severe |
Severe acute chorioamnionitis or with subchorionic microabscesses. Confluent PMN (> 10 x 20 cells in extent) between chorion and decidua; > 3 isolated foci or continuous band |
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Other |
Chronic (or subacute) chorioamnionitis |
Subamnionic mononuclear cell infiltrate with occasional PMN (meconium and hemosiderin-laden macrophages excluded) |
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