Specimen Triage

*Specimen Triage


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A - Z List

                       Conditions for Pathology Specimen Submission

Purpose

Parts

Size/Quant

Fixative

Sterile

Storage

Transport

Laboratory

Routine Histopathology


> 1 x 1 mm

Yes

(formalin)

NR

RT


Surgical Pathology Lab

Mircoorganism Culture

1


No

Yes

RT

ASAP

Microbiology Lab

2


Yes

NR



Surgical Pathology Lab

Immuno-

flurescence

1


Yes

NR




2


No

NR

Freeze



Electron Microscopy


2 x < 0.5 mm

Yes

Glutaldehyde

NR

4 C


EM Lab

Cytogenetics

(solid tumor)

1

> 5 x 5 mm

Yes

NR

RT



2

5 x 5 mm

No

Yes

RT

ASAP

Cytogenetics Lab

Flow Cytometry

1


Yes

NR

RT



1


No

Yes

4 C

ASAP


       Abbrev:  ASAP = as soon as possible; EM = Electron Microscopy; NR = not required; RT = room temperature;


               Specimen Triage for Special Diagnostic Studies in Pathology

Diagnosis / Studies

Routine

Histology

Tissue

Culture

Flow

Cytometry

Immuno-

fluorescence

Electron

Microscopy

Cyto-

genetics


Comment










Lymphoma

++


++



+


All except Hodgkins lymphoma

Leukemia

++


++



+



Infectious disease

++

++



+/-




Mycobacteria

++

++







Whipples disease

++




++




Cytomegalovirus

++








Herpes









Cervical HPV

++







PCR

C. diff colitis

++







Serology

Skin bullous disease

+



++





Mesothelioma

++




++




PD carcinoma

++




+

++



Soft tissue sarcomas

++




+

++




Abbrev:  PCR = polymerase chain reaction; PD = poor differentiated (carcinomas); HPV = human papilloma virus.